Elevated blood pressure, with and without pre-existing hypertension, has been reported following administration of Fentanyl Citrate Injection combined with a neuroleptic.
There is increased risk in patients whose ability to maintain blood pressure has already been compromised by a reduced blood volume or concurrent administration of certain CNS depressant drugs (e.g., phenothiazines or general anesthetics) see Drug Interactions (7). .The onset of action of fentanyl is almost immediate when the drug is given intravenously; however, the maximal respiratory depressant effect may not be noted for several minutes.As an opioid, Fentanyl, citrate Injection exposes users to the risks of addiction, abuse, and misuse see.At, or the FDA at 1-800-FDA-1088 or www.The respiratory depression involves a reduction in the responsiveness of the brain stem respiratory centers to both increases in carbon dioxide tension and electrical stimulation.Patient Counseling Information Serotonin Syndrome Inform patients that Fentanyl Citrate Injection could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. .Clinical Considerations Fetal/Neonatal Adverse Reactions Prolonged use of opioid analgesics during pregnancy for medical or nonmedical purposes can pokemon gold emulator rom for vba result in physical dependence in the neonate and neonatal opioid withdrawal syndrome shortly after birth.Contact local state professional licensing board or state controlled substances authority for information on how to prevent and detect abuse or diversion of this product.Limit dosages and durations to the minimum required.Physical dependence may not occur to a clinically significant degree until after several days to weeks of continued opioid usage.To reduce the risk of respiratory depression, proper dosing and titration of Fentanyl Citrate Injection are essential.
Expect the need of postoperative ventilation and observation due to extended post-operative boy scout troop committee handbook respiratory depression.
As postoperative analgesia, concomitant use of Fentanyl Citrate Injection can increase the risk of hypotension, respiratory depression, profound sedation, coma, and death.
If adrenal insufficiency is suspected, confirm the diagnosis with diagnostic testing as soon as possible.Show On This Page, view All.It is all too common for those using methamphetamine to overdose on the stimulant.If adrenal insufficiency is diagnosed, treat with physiologic replacement doses of corticosteroids.Expect respiratory depression requiring artificial ventilation during anesthesia and careful observation of ventilation postoperatively is essential.
For open heart surgery and certain more complicated neurosurgical and orthopedic procedures where surgery is more prolonged, and the stress response to surgery would be detrimental to the well-being of the patient.
Maintenance Dose (expressed as fentanyl base) Low Dose2 mcg/kg (0.002 mg/kg) (0.04 mL/kg).